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Ozone therapy is a form of oxidative medicine that attempts to isolate and destroy bacteria, parasites, and viruses through exposure to ozone, a molecule composed of three oxygen atoms. The basis for ozone therapy relies on the body’s own antimicrobial defense systems – as oxygen is metabolized in our cells, cell-damaging oxidants are set free as byproducts. When weaponized medically, oxidation may combat disease carriers. 

Oxygen plays a crucial role in biology, but metabolizing oxygen releases reactive oxygen species, which can cause cell damage. Ozone works in much the same way, which is why ozone therapy must be administered carefully. Direct administration of ozone gas through injection or inhalation, for example, can be toxic and is not recognized nor recommended as a medical treatment method. Ozonation of different tissues or blood, on the other hand, may result in improved outcomes for conditions such as Lyme disease. 

Let’s dig into how ozone therapy works, its benefits, and its different applications in medicine. 

What is Ozone Therapy?

Ozone therapy is a form of alternative medicine that involves administering ozone molecules into the body to treat various medical conditions or treating blood with ozone. Ozone (O3) is a molecule composed of three oxygen atoms, whereas the oxygen we breathe (O2) consists of two atoms. 

Excessive exposure to ozone is harmful. However, we believe that introducing ozone into the body through a controlled manner can stimulate the immune system, improve oxygen delivery to tissues, and have antimicrobial, antiviral, and antibacterial effects. 

Ozone-based treatments are not new. Ozone therapies have been in use since the 1970s, and the complication rate for ozone therapies is low, estimated at less than 1 per 100,000 treatments. When administered safely, ozone therapy can be a useful treatment tool for arthritis, bacterial infections, disc herniations, diabetic neuropathy, and other diagnoses. 

Ozone Therapy Benefits

Oxidative medicine, including treatments like ozone therapy, can be an alternative approach to treating Lyme disease and other similar conditions. The ozone therapy benefits include: 

  • Oxygenation and Immune Stimulation: Increasing oxygen levels in tissues may enhance immune function, potentially aiding in the body’s ability to combat infections.
  • Reduced oxidative stress: Oxidative stress is generally the result of an imbalance between cell-damaging reactive oxygen species and antioxidant compounds/enzymes in the body. Ozone therapy may help play a role in correcting that imbalance, which can reduce oxidative stress and related inflammatory responses. 
  • Antimicrobial Effects: Ozone therapy may have direct antimicrobial properties. It may help in killing or inhibiting the growth of bacteria, and the proliferation of viruses or parasites. 
  • Treatment of herniated discs: Ozone therapy showed an improvement in symptoms among patients with herniated discs, wherein the spinal discs between the vertebrae enlarge due to physical stress or disc degeneration, causing nerve impingement and related nerve pain. Other common forms of ozone-related spinal disc treatment include ozone chemonucleolysis. 
  • Neuropathic treatment: When administered in the treatment of degenerative nerve diseases, oxidative stress carefully modulated through ozone therapy resulted in the activation of key pathways suppressing inflammatory processes and correcting the nerve damage caused by diabetes. 
  • Supporting Overall Health: Oxidative therapies can support overall health by improving cellular function and reducing inflammation, which may indirectly benefit Lyme disease patients.

Current mainstream treatments for Lyme disease typically involve antibiotics prescribed by healthcare providers following established guidelines, and within a limited timeframe. 

There are no recognized or established guidelines for the long-term treatment of chronic Lyme disease, and some previously popular treatments – such as long-term antibiotic treatment courses – carry a significant risk to a patient’s overall health and well-being. Ozone therapy can serve as an alternative treatment course, aiming to eliminate any remaining spirochetes still active within a person after a B. burgdorferi infection through ozone’s germicidal properties.


ozone therapy benefits - Lyme Mexico


Different Types of Ozone Therapy

Ozone can be introduced into the body through a variety of ways. Different treatment methods are used for different conditions, depending on the aim of the treatment. In most cases, ozone is introduced to the body either via the blood, or via insufflation. 

Direct injections of ozone gas into the bloodstream are usually avoided, due to the risk of gas embolisms. Direct exposure to ozone in the lungs can also cause lasting damage to the throat and lungs, including acute respiratory problems and pulmonary edema. Self-administering ozone is not recommended. Instead, consider ozone therapy through a certified and professional clinician. 

Different forms of ozone therapy include: 

Ozone Hemotherapy

Ozone hemotherapy involves drawing blood and infusing the blood with ozone and an anticoagulant solution, before returning the ozonated blood back into the patient intravenously. Upon exposure to ozone within the blood, potentially harmful bacteria or remaining inactive bacteria are neutralized, and the ozone is metabolized into oxygen. Because the process of ozonation occurs outside of the body and the gas isn’t injected into any blood vessels, the risk of a gas embolism is eliminated. 

Ozone Insufflation

Ozone may also be administered via insufflation through any body cavities with a mucous membrane – usually via rectal or vaginal insufflation. In these cases, the ozone gas enters the body through an enema, and it is absorbed by the colon walls or the vaginal walls, entering the bloodstream. In dentistry, oral insufflation directly into the gums is becoming more common as a clinical tool in periodontology, endodontics, and oral surgery.  

Ozone-Charged Drinking Water

While ingestion of large amounts of ozone is not advisable, medically-supervised ingestion of low levels of ozonated water may have therapeutic benefits. 

Ozone Injection

Ozonated water may also be injected intraperitoneally (into the body cavity) to elicit a greater therapeutic benefit in the treatment of an acute inflammatory response. Ozone injections into joints can also help alleviate pain through the same anti-inflammatory response observed in the treatment of herniated discs and oxidative neuropathy. 


Ozone therapy is a form of oxidative medicine that uses ozone to treat medical conditions related to inflammatory and oxidative stress, as well as bacterial infections. It involves introducing ozone into the body to harness its antimicrobial and immune-stimulating properties. Administered carefully, it can improve oxygen delivery to tissues and has been used for conditions like arthritis, bacterial infections, and Lyme disease, among others.

Consider traveling outside of the country to meet with a top clinic, Lyme Mexico. The Lyme Mexico Clinic can meet all your diagnostic and treatment needs. Learn more about Lyme disease or schedule an evaluation. We can discuss your symptoms and the alternative treatment options that work.


ozone therapy benefits - Lyme Mexico

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